QJEEM22Ch4d6f: JEE Main 2022 Chemistry - Class 12 JEEM22Ch4d6f Solution: Two statements in respect of drug-enzyme interaction are given…
Two statements in respect of drug-enzyme interaction are given below
Statement I : Action of an enzyme can be blocked only when an inhibitor blocks the active site of the enzyme.
Statement II : An inhibitor can form a strong covalent bond with the enzyme.
In the light of the above statements, choose the correct answer from the options given below
Multiple Choice Options
- A Both Statement I and Statement II are true
- B Both Statement I and Statement II are false
- C Statement I is true but Statement II is false
- D Statement I is false but Statement II is true
Step-by-Step Verified Solution
Let's analyze both statements:
Statement I: Action of an enzyme can be blocked only when an inhibitor blocks the active site of the enzyme. This statement is false because enzyme inhibition can occur in more than one way. Besides competitive inhibition (where the inhibitor binds to the active site), there are other types such as non-competitive and uncompetitive inhibition, where the inhibitor can bind elsewhere on the enzyme, altering its function.
Statement II: An inhibitor can form a strong covalent bond with the enzyme. This statement is true. Some inhibitors, known as irreversible inhibitors, form strong covalent bonds with the enzyme, permanently inactivating it.
So the correct answer is:
Option D: Statement I is false but Statement II is true.