Verified Solution • 2025–26 Session
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QJEEM21Che706: JEE Main 2021 Chemistry - Class 12 JEEM21Che706 Solution: With respect to drug-enzyme interaction, identify the wrong…
With respect to drug-enzyme interaction, identify the wrong statement.
Multiple Choice Options
- A Allosteric inhibitor changes the enzyme's active site
- B Allosteric inhibitor competes with the enzyme's active site
- C Competitive inhibitor binds to the enzyme's active site
- D Non-Competitive inhibitor binds to the allosteric site
Step-by-Step Verified Solution
Allosteric inhibitor combines at allosteric site and not the active site.
Drugs inhibit the attachment of substrate on active site of enzymes in two different ways :
(i) Drugs compete with the natural substrate for their attachment on the active sites of enzymes. Such drugs are called competitive inhibitors.
(ii) Some drugs do not bind to the enzyme's active site. These bind to a different site of enzyme which is called allosteric site. This binding of inhibitor at allosteric site changes the shape of the active site in such a way that substrate cannot recognise it.This is also called non-competitive inhibitor.
Non-competitive inhibitor changes the active site of enzyme after binding at allosteric site.